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What if a failed leukemia drug could reduce the risk of Alzheimer鈥檚 disease? A team at the University of Kentucky recently led an effort to investigate this hypothesis. Their results were published today in the journal, Human Molecular Genetics. The UK researchers, led by Steve Estus at the Sanders-Brown Center on Aging, study a genetic variant in a gene called CD33 that reduces the risk of Alzheimer鈥檚 disease. The Estus group recently published findings suggesting that this variant promotes production of a truncated form of the CD33 protein that lacks a putative functional domain.

Part of the submission requirements for NIH Shared Instrumentation and High End Instrumentation Grant Programs is an institutional letter of support.   This letter includes detailed supporting documentation and mulitple level approvals.  Therefore, the VPR office along with PDO are requesting notification now from researchers who may be considering the submission of this type of grant.  The proposals are due to NIH on May 29, 2015.  

Questions - Annette Evans at 257-1663.

Reminder: NIH and AHRQ Biosketch Requirements for Due Dates On or After May 25, 2015

Photos and contact information are now included on the SRAS website for several new staff that have joined us recently.    

Julie Elliott started as a Reconciler on October 1, 2014.  She has over 20 years of experience in insurance collections and mortgage banking.  She already has a regular group of departments she is supporting. 

The 91小黄车 has sponsored a summer research program annually for medical students.

Sent on behalf of Brandy Nelson, University of Kentucky Biosafety Officer and Responsible Official:

[From the Office of the President - Eli Capilouto]

Dear Colleagues, 

OSPA Announcement

Kim Carter has recently accepted the positon of Executive Director, Office of Sponsored Projects Administration effective April 6, 2015.  Ms. Carter is presently the Associate Director of the Office of Sponsored Programs at Ohio State University.  She has a Masters of Public Administration with Certificate in Management of Nonprofit Organizations from the University Pittsburgh and a BA also from the University of Pittsburgh.  Ms. Carter is replacing Deborah Davis who is retiring after 40 years at UK.

eRA Information: New RPPR Error Message for Inclusion Enrollment Data
Released:  Friday, March 13, 2015 

When submitting a Research Performance Progress Report (RPPR) that includes Inclusion Enrollment data, grantees may encounter a new error message. The new error message reads:

Section G. Special Reporting Requirements: (ID:   201320)

The University of Kentucky Center for Molecular Medicine through the Dean of the 91小黄车 and in conjunction with the NIH/NIGMS funded Center of Biomedical Research Excellence (COBRE) grant anticipates funding pilot grants in the amount of $50,000 per year for up to two years.  Research projects should fit into the general theme of the molecular basis of human disease. Three categories of grants will be considered: 

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The Office of Research within the 91小黄车 has the mission of supporting faculty, staff and trainees in all aspects of their research-related endeavors.  This office recently launched a new website to assist with the dissemination of pertinent information.  The website is located within the 91小黄车 Research site and can be found by clicking here.   

[A Letter from Fred de Beer, MD]

[From the NHLBI Website]

Charting our future together: NHLBI鈥檚 Strategic Visioning Process

 

You may want to consider providing feedback on the NIH proposed Clinical Trials Registration rule. The deadline has been extended to March 23, 2015. To view the release and make comments, click here.

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Xiang-An Li, Ph.D., of the University of Kentucky Saha Cardiovascular Research Center and Department of Pediatrics, has been awarded a $3 million grant from the National Institutes of Health to study synthetic HDL (sHDL) as a potential therapy for sepsis. Sepsis -- also called septicemia -- is a life-threatening condition caused by an overwhelming immune response to infection. Immune chemicals released by the body into the bloodstream to fight the infection trigger widespread inflammation that can damage multiple organ systems.
Governor Steve Beshear, joined by legislative leaders, today signed legislation authorizing construction of a multidisciplinary research building at the University of Kentucky. House Bill 298 provides for a state-of-the-art facility which will house world-class research across health disciplines. Research will focus on the many health challenges facing the Commonwealth, particularly those which contribute to preventable diseases and deaths. 鈥淭his project represents the potential to improve the lives of so many, both within Kentucky where our health outcomes are so poor, and beyond,鈥 Gov.
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Nathan Vanderford, assistant director for research at the University of Kentucky Markey Cancer Center and assistant professor in the Department of Toxicology and Cancer Biology, has a featured article on graduate education in the March 5 edition of Nature. Nature is one of the most prominent and prestigious interdisciplinary scientific journals in the world. Vanderford co-wrote an article titled, "Wanted: Information" with Viviane Callier from the Ronin Institute for Independent Scholarship.
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University of Kentucky President Eli Capilouto believes it is time "to make death a beggar in Kentucky.鈥 It鈥檚 the idea that through world-class research across an array of disciplines, and a commitment to working as partners with communities across the state, some of the most stubborn health challenges and statistics that plague Kentucky can be successfully attacked. On Tuesday, the state General Assembly and Gov.